Adolescent electronic cigarette use and tobacco smoking in the Millennium Cohort Study

E-cigarette use by age 14 is associated with increased odds of smoking initiation and frequent smoking at age 17.

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Effect of extended-release naltrexone on alcohol consumption: a systematic review and meta-analysis

Extended-release naltrexone reduces drinking days and heavy drinking days per month compared with placebo.

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Weeding out the truth: a systematic review and meta-analysis on the transition from cannabis use to opioid use and opioid use disorders, abuse or dependence

There is low-quality evidence that people who use cannabis are more likely to initiate opioid use and engage in problematic patterns of use.

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