Key Findings

This is a quick summary of the main discovery for each research paper we have published, organized issue by issue. Each key finding is below the article title, with a link to the abstract. 


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December 2019

Pharmacotherapy for methamphetamine/amphetamine use disorder—a systematic review and meta‐analysis

Most medications for methamphetamine/amphetamine use disorder have not shown a statistically significant benefit but there is low‐strength evidence that methylphenidate may reduce use.

Link to Abstract

Effects of repetitive transcranial magnetic stimulation (rTMS) on craving and substance consumption in patients with substance dependence: a systematic review and meta‐analysis

Excitatory repetitive transcranial magnetic stimulation (rTMS) of the dorsolateral pre‐frontal cortex appears to have an acute effect on reducing substance craving and consumption in patients with substance dependence.

Link to Abstract

Changes in associations of prescription opioid use disorder and illegal behaviors among adults in the United States from 2002 to 20

In the US from 2002-2014, rates of some crimes potentially related to drug use increased among people with prescription opioid use disorder compared with those without that disorder.

Link to Abstract

Trajectories of injection drug use among people who use drugs in Vancouver, Canada, 1996–2017: growth mixture modeling using data from prospective cohort studies

People who used drugs in Vancouver, Canada from 1996 to 2017 appeared to follow one of five drug use trajectories ranging from persistent high frequency use to early cessation. Almost 25% of participants remained high‐frequency injectors over the study period.

Link to Abstract

Associations between young adult marijuana outcomes and availability of medical marijuana dispensaries and storefront signage

Living near more medical marijuana dispensaries is positively associated with more frequent use of marijuana within the past month and greater expectations of marijuana's positive benefits than living near fewer dispensaries.

Link to Abstract

Risky driving behaviours among stimulant drug users and the role of aggression: findings from a national survey

Stimulant use appears to be positively associated with risky driving behaviours even after adjusting for aggressiveness.

Link to Abstract

Perceived relative harm of using e‐cigarettes predicts future product switching among US adult cigarette and e‐cigarette dual users

US adult dual users of e‐cigarettes and cigarettes who perceive e‐cigarettes as less harmful than cigarettes appear to be more likely to switch to exclusive e‐cigarette use 1 year later than dual users with other perceptions.

Link to Abstract

Cost‐effectiveness of population‐level proactive tobacco cessation outreach among socio‐economically disadvantaged smokers: evaluation of a randomized control trial

Population‐level proactive tobacco treatment with personal telephone outreach was effective in achieving higher quit rates and was cost‐effective at various willingness‐to‐pay thresholds compared with usual care.

Link to Abstract

Schizophrenia is associated with increased risk of subsequent substance abuse diagnosis: A nation‐wide population‐based register study

In Denmark a diagnosis of schizophrenia is significantly associated with increased risk of subsequent diagnosis of substance abuse.

Link to Abstract

Genetic and environmental risk factors in the non‐medical use of over‐the‐counter or prescribed analgesics, and their relationship to major classes of licit and illicit substance use and misuse in a population‐based sample of young adult twins

In Australian young adults, the non‐medical use of analgesics appears to have moderate heritability and is associated with cannabis and nicotine use and nicotine dependence.

Link to Abstract

Association between experience of racial discrimination and hazardous alcohol use among Māori in Aotearoa New Zealand

The association between Māori ethnicity and hazardous drinking in New Zealand may be partially mediated by experience of discrimination.

Link to Abstract

Comparison of e‐cigarette use characteristics between exclusive e‐cigarette users and dual e‐cigarette and conventional cigarette users: an on‐line survey in France

Dual e‐cigarette users in France may have higher nicotine intake overall than exclusive e‐cigarette users, but they may take in less nicotine from their e‐cigarettes.

Link to Abstract

Assessment of the accuracy of salivary cotinine readings from NicAlert strips against a liquid chromatography tandem mass spectrometry assay in self‐reported non‐smokers who passed carbon monoxide but failed NicAlert validation

In participants in a randomized trial, NicAlert saliva tests incorrectly classified a high proportion of non-smokers as smokers.

Link to Abstract

Adding quality to quantity in randomized controlled trials of addiction prevention and treatment: a new framework to facilitate the integration of qualitative research

The ‘temporal parallel purpose framework’ provides a tool for combining qualitative research with treatment and prevention RCTs.

Link to Abstract

Cost‐effectiveness of scaling‐up HCV prevention and treatment in the United States for people who inject drugs

Hepatitis C screening and treatment for people who inject drugs, combined with medication‐assisted treatment and syringe‐service programs, is a cost‐effective strategy to reduce the hepatitis C burden in the US.

Link to Abstract