Key Findings

This is a quick summary of the main discovery for each research paper we have published, organized issue by issue. Each key finding is below the article title, with a link to the abstract. 


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August 2016

The effects of cannabis intoxication on motor vehicle collision revisited and revised

Acute cannabis intoxication is associated with a small but statistically significant increase in motor vehicle crash risk.

Link to Abstract

Topiramate for cocaine dependence: a systematic review and meta-analysis of randomized controlled trials

Current evidence does not support the use of topiramate to improve treatment retention for cocaine use disorder.

Link to Abstract

Gender-specific effects of comorbid depression and anxiety on the propensity to drink in negative emotional states

Female alcoholics seem to have a higher prevalence than males of comorbid depression and anxiety disorders and tendency to drink in negative emotional situations.

Link to Abstract

Daily alcohol use as an independent risk factor for HIV seroconversion among people who inject drugs

Daily alcohol use appears to be an independent risk factor for HIV seroconversion among people who inject drugs.

Link to Abstract

A randomized trial of a pain management intervention for adults receiving substance use disorder treatment

Among adults with pain receiving addictions treatment, a psychological pain management intervention appears to reduce pain and alcohol use and improve pain-related functioning over 12 months.

Link to Abstract

Estimating demand for primary care-based treatment for substance and alcohol use disorders

In the US, people with substance or alcohol use disorders seem more willing to enter treatment in a primary care setting than in a specialty drug treatment centre.

Link to Abstract

Buprenorphine + naloxone plus naltrexone for the treatment of cocaine dependence: the Cocaine Use Reduction with Buprenorphine (CURB) study

Buprenorphine + naloxone, used in combination with naltrexone, may be associated with reductions in cocaine use among people with cocaine dependence.

Link to Abstract

A randomized controlled trial of buprenorphine taper duration among opioid-dependent adolescents and young adults

Longer (56-day) buprenorphine taper produces better opioid abstinence and retention outcomes than shorter (28-day) taper for opioid-dependent youth.

Link to Abstract

Effectiveness of a universal internet-based prevention program for ecstasy and new psychoactive substances: a cluster randomized controlled trial

A universal online school-based prevention program appeared to reduce students' intentions to use new psychoactive substances (NPS) and increased knowledge about ecstasy and NPS in the short term.

Link to Abstract

Depression motivates quit attempts but predicts relapse: differential findings for gender from the International Tobacco Control Study

Smokers with depressive symptoms or diagnosis make more quit attempts than their non-depressed counterparts but are likelier to relapse in the first month.

Link to Abstract

Problem gambling and the five-factor model of personality: a large population-based study

Higher severity problem gambling may be associated with higher neuroticism scores and lower conscientiousness and agreeableness scores in the Mini-International Personality Item Pool.

Link to Abstract

Adolescent smoking and tertiary education: opposing pathways linking socio-economic background to alcohol consumption

In Britain, young adults are more likely to drink heavily both if they smoke and if they participate in tertiary education (college and university).

Link to Abstract

The impact of quitting smoking on depressive symptoms: findings from the International Tobacco Control Four-Country Survey

Most people who stop smoking appear to be at no greater risk of developing symptoms of depression than if they had continued smoking.

Link to Abstract

Ecological momentary assessment of working memory under conditions of simultaneous marijuana and tobacco use

The putative effect of marijuana on working memory and the facilitative effect of tobacco on working memory are no longer present when used simultaneously with tobacco and alcohol, respectively.

Link to Abstract

Weak evidence on nalmefene creates dilemmas for clinicians and poses questions for regulators and researchers

Nalmefene, a drug used to treat alcohol problems, was licensed for use in the UK despite insufficient evidence to prove its effectiveness.

Link to Abstract