Key Findings

This is a quick summary of the main discovery for each research paper we have published, organized issue by issue. Each key finding is below the article title, with a link to the abstract. 


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January 2018

Mecamylamine treatment for alcohol dependence: a randomized controlled trial

Mecamylamine did not reduce alcohol consumption significantly in either treatment-seeking smokers or non-smokers with alcohol use disorder.

Link to Abstract

Major life events and risk of alcohol use disorders: a prospective cohort study

There is a strong association between serious economic problems in adult life and risk of alcohol use disorders.

Link to Abstract

Prediction of alcohol use disorder using personality disorder traits: a twin study

Conduct disorder and self-harming impulsivity are the foremost risk traits for alcohol use disorder among the 80 personality disorder criteria of DSM-IV.

Link to Abstract

Childhood traumatic experiences and the association with marijuana and cocaine use in adolescence through adulthood

In the US, childhood trauma (individual types and total number experienced) is significantly associated with marijuana and cocaine use throughout life.

Link to Abstract

The stability of baseline-defined categories of alcohol consumption during the adult life-course: a 28-year prospective cohort study

Among UK civil servants, alcohol consumption within baseline drinking categories is generally stable during the life-course, except among heavier baseline drinkers, for whom intakes decline with increasing age.

Link to Abstract

To take or not to take: the association between perceived addiction risk, expected analgesic response and likelihood of trying novel pain relievers in self-identified chronic pain patients

In the US, self-identified chronic pain patients (CPP) at higher risk for opioid misuse are more likely to report willingness to try a novel analgesic despite increasing addiction risk than CPP with low risk of opioid misuse.

Link to Abstract

Risk factors for severe respiratory depression from prescription opioid overdose

The severity of symptoms in people attending US emergency departments because of prescription opioid overdose varied widely with the type of opioid and was worse in substance misusers and older patients.

Link to Abstract

The relationship between gambling expenditure, socio-demographics, health-related correlates and gambling behaviour—a cross-sectional population-based survey in Finland

In Finland, men spend more than women on gambling relative to net income. Those on lower incomes spend proportionately more of their income on gambling than those on higher incomes.

Link to Abstract

Association between universal hepatitis B prison vaccination, vaccine uptake and hepatitis B infection among people who inject drugs

In Scotland, uptake of hepatitis B virus vaccination among people in the community who inject drugs has increased since the 1999 introduction of universal prison vaccination.

Link to Abstract

Adult interest in using a hypothetical modified risk tobacco product: findings from wave 1 of the Population Assessment of Tobacco and Health Study (2013–14)

Among US adults, interest in using a hypothetical modified risk tobacco product is low overall, and highest among current experimental and established smokers.

Link to Abstract

Self-changing behaviour in smoking cessation linked to trait and cognitive impulsivity

Among smokers who do not seek treatment to help them stop, those who succeed in stopping appear to have a lower tendency to act on impulse and inhibit thoughts than those who continue to smoke.

Link to Abstract

Effects of comorbid substance use disorders on outcomes in a Housing First intervention for homeless people with mental illness

Housing First programmes in Canada for people who are experiencing homelessness and mental illness are equally effective in people with and without comorbid substance use disorder (SUD).

Link to Abstract

German EstSmoke: Estimating adult smoking-related costs and consequences of smoking cessation for Germany

Life-time healthcare costs of German smokers appear to be substantially greater than those of German nonsmokers.

Link to Abstract

Effects of high alcohol intake, alcohol-related symptoms and smoking on mortality

The number of symptoms related to high alcohol intake and smoking appears to account for the positive association between alcohol consumption and early death.

Link to Abstract

Associations of coffee genetic risk scores with consumption of coffee, tea and other beverages in the UK Biobank

Coffee-related genetic risk scores could be used as instrumental variables indexing combined coffee and tea consumption in Mendelian randomization studies.

Link to Abstract

Scaling-up HCV prevention and treatment interventions in rural United States— model projections for tackling an increasing epidemic

To decrease hepatitis C virus (HCV) incidence and prevalence in rural Indiana, USA, by 90% by 2025/30, both HCV treatment and prevention interventions must be increased.

Link to Abstract