Key Findings

This is a quick summary of the main discovery for each research paper we have published, organized issue by issue. Each key finding is below the article title, with a link to the abstract. 


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May 2019

Modelling continuous abstinence rates over time from clinical trials of pharmacological interventions for smoking cessation

Continuous abstinence rates in clinical trials of smoking cessation pharmacotherapies can be modelled to allow accurate prediction of abstinence rates up to 52 weeks from end of treatment.

Link to Abstract

Income trajectories prior to alcohol‐attributable death in Finland and Sweden

In Finland and Sweden, income appears to decline substantially before alcohol‐attributable death.

Link to Abstract

Blunted stress reactivity reveals vulnerability to early life adversity in young adults with a family history of alcoholism

People with a family history of alcoholism appear to be more vulnerable to the impact of exposure to early life adversity on stress responsiveness compared with people with no family history of alcoholism.

Link to Abstract

Young cohorts of Russians drink less: age–period–cohort modelling of alcohol use prevalence 1994–2016

The recent downward trend in alcohol use in Russia appears to be attributable to reduced participation rates among younger cohorts born after 1990.

Link to Abstract

Neighborhood density of alcohol outlets moderates genetic and environmental influences on alcohol problems

People who are genetically predisposed to develop alcohol problems may be especially sensitive to the influence of alcohol outlet density in their community.

Link to Abstract

Traffic fatalities within US states that have legalized recreational cannabis sales and their neighbours

In the first year of legalized recreational cannabis in Washington, Oregon, and Colorado, traffic fatalities temporarily increased by an average of one more per million residents in those states and their neighbouring states.

Link to Abstract

Birth cohort effects on the quantity and heritability of alcohol consumption in adulthood: a Finnish longitudinal twin study

The contribution of genetic and environmental variability to variability in alcohol consumption in the Finnish population appears to vary by birth cohort.

Link to Abstract

Chronic obstructive pulmonary disease (COPD) among opioid‐dependent patients in agonist treatment. A diagnostic study

People in opioid dependence treatment have higher rates of chronic obstructive pulmonary disease than the general population.

Link to Abstract

Pharmacokinetics of a novel, approved, 1.4‐mg intranasal naloxone formulation for reversal of opioid overdose—a randomized controlled trial

Intranasal 1.4 mg naloxone appears to provide adequate systemic concentrations to treat opioid overdose.

Link to Abstract

Finding smoking hot‐spots: a cross‐sectional survey of smoking patterns by housing tenure in England

People living in publicly-owned or housing-association housing are much more likely to be smokers, even after adjusting for poverty and other socio-economic factors. These smokers are more motivated to stop than other smokers but find it more difficult.

Link to Abstract

Harm perceptions of e‐cigarettes and other nicotine products in a UK sample

Large proportions of UK smokers and ex‐smokers overestimate the relative harmfulness of e‐cigarettes and NRT compared with smoking.

Link to Abstract

Vaping characteristics and expectancies are associated with smoking cessation propensity among dual users of combustible and electronic cigarettes

Among e‐cigarette users who also smoke cigarettes, more frequent vaping is associated with greater likelihood of later quitting smoking while enthusiasm for vaping, higher nicotine content in e-cliquid, and use of tobacco-flavoured solution is associated with lower likelihood of quitting.

Link to Abstract

Patterns and correlates of polysubstance use among US youth aged 15–17 years: wave 1 of the Population Assessment of Tobacco and Health (PATH) Study

Among US youth aged 15–17 years, substance use is correlated with higher sensation‐seeking, poor academic performance, non‐urban residence, minority sexual orientation and mental health problems.

Link to Abstract