Published since 1884 by the Society for the Study of Addiction.
Editor-in-Chief, Robert West

This is a quick summary of the main discovery for each research paper we have published, organized issue by issue. The article titles are in bold and each key finding is below the article title.  Use the filters below to isolate key findings for each issue or search for a particular topic across all of this year's issues.

January 2018

Mecamylamine treatment for alcohol dependence: a randomized controlled trial

Mecamylamine did not reduce alcohol consumption significantly in either treatment-seeking smokers or non-smokers with alcohol use disorder.

Link to Abstract
Prediction of alcohol use disorder using personality disorder traits: a twin study

Conduct disorder and self-harming impulsivity are the foremost risk traits for alcohol use disorder among the 80 personality disorder criteria of DSM-IV.

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Major life events and risk of alcohol use disorders: a prospective cohort study

There is a strong association between serious economic problems in adult life and risk of alcohol use disorders.

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The stability of baseline-defined categories of alcohol consumption during the adult life-course: a 28-year prospective cohort study

Among UK civil servants, alcohol consumption within baseline drinking categories is generally stable during the life-course, except among heavier baseline drinkers, for whom intakes decline with increasing age.

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Childhood traumatic experiences and the association with marijuana and cocaine use in adolescence through adulthood

In the US, childhood trauma (individual types and total number experienced) is significantly associated with marijuana and cocaine use throughout life.

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Risk factors for severe respiratory depression from prescription opioid overdose

The severity of symptoms in people attending US emergency departments because of prescription opioid overdose varied widely with the type of opioid and was worse in substance misusers and older patients.

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To take or not to take: the association between perceived addiction risk, expected analgesic response and likelihood of trying novel pain relievers in self-identified chronic pain patients

In the US, self-identified chronic pain patients (CPP) at higher risk for opioid misuse are more likely to report willingness to try a novel analgesic despite increasing addiction risk than CPP with low risk of opioid misuse.

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Association between universal hepatitis B prison vaccination, vaccine uptake and hepatitis B infection among people who inject drugs

In Scotland, uptake of hepatitis B virus vaccination among people in the community who inject drugs has increased since the 1999 introduction of universal prison vaccination.

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The relationship between gambling expenditure, socio-demographics, health-related correlates and gambling behaviour--a cross-sectional population-based survey in Finland

In Finland, men spend more than women on gambling relative to net income. Those on lower incomes spend proportionately more of their income on gambling than those on higher incomes.

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Self-changing behaviour in smoking cessation linked to trait and cognitive impulsivity

Among smokers who do not seek treatment to help them stop, those who succeed in stopping appear to have a lower tendency to act on impulse and inhibit thoughts than those who continue to smoke.

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Adult interest in using a hypothetical modified risk tobacco product: findings from wave 1 of the Population Assessment of Tobacco and Health Study (2013-14)

Among US adults, interest in using a hypothetical modified risk tobacco product is low overall, and highest among current experimental and established smokers.

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German EstSmoke: Estimating adult smoking-related costs and consequences of smoking cessation for Germany

Life-time healthcare costs of German smokers appear to be substantially greater than those of German nonsmokers.

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Effects of comorbid substance use disorders on outcomes in a Housing First intervention for homeless people with mental illness

Housing First programmes in Canada for people who are experiencing homelessness and mental illness are equally effective in people with and without comorbid substance use disorder (SUD).

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Associations of coffee genetic risk scores with consumption of coffee, tea and other beverages in the UK Biobank

Coffee-related genetic risk scores could be used as instrumental variables indexing combined coffee and tea consumption in Mendelian randomization studies.

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Effects of high alcohol intake, alcohol-related symptoms and smoking on mortality

The number of symptoms related to high alcohol intake and smoking appears to account for the positive association between alcohol consumption and early death.

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Scaling-up HCV prevention and treatment interventions in rural United States-- model projections for tackling an increasing epidemic

To decrease hepatitis C virus (HCV) incidence and prevalence in rural Indiana, USA, by 90% by 2025/30, both HCV treatment and prevention interventions must be increased.

Link to Abstract

February 2018 – Current Issue

Pharmacologically controlled drinking in the treatment of alcohol dependence or alcohol use disorders

Evidence is inconclusive for using nalmefene, naltrexone, acamprosate, baclofen or topiramate to control drinking in patients with alcohol dependence or alcohol use disorder.

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Using Bayes factors to evaluate evidence for no effect: examples from the SIPS project

Scientists who find non-significant results should calculate a Bayes factor to determine if there is evidence for a null hypothesis over an alternative hypothesis or that more data are needed.

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New cancer cases in France in 2015 attributable to different levels of alcohol consumption

Alcohol consumption in France appears to cause almost 8% of new cancer cases, with light and moderate drinking contributing appreciably to this burden.

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Associations between adolescent cannabis use and neuropsychological decline: a longitudinal co-twin control study

Adolescent cannabis use does not cause a decline in IQ, even when that use reaches dependence.

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Extended-release naltrexone for methamphetamine dependence among men who have sex with men: a randomized placebo-controlled trial

Extended-release naltrexone does not appear to reduce methamphetamine use or sexual risk behaviors among methamphetamine-dependent men who have sex with men.

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Does paying service providers by results improve recovery outcomes for drug misusers in treatment in England?

Drug addiction recovery services in England commissioned on a payment-by-results basis tend to have lower rates of treatment initiation and completion but higher rates of in-treatment abstinence and non-injecting than other services.

Link to Abstract
Luck, come here! Automatic approach tendencies toward gambling cues in moderate- to high-risk gamblers

In the Netherlands, moderate- to high-risk gamblers appear to have a stronger tendency than non-problem gamblers to show an 'approach' tendency in a laboratory task to gambling-related pictures compared with neutral pictures. This gambling approach bias has been found to predict persistence in gambling behaviour over time.

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Ecological momentary analysis of the relations among stressful events, affective reactivity, and smoking among smokers with high versus low depressive symptoms during a quit attempt

Depressed smokers experience more exposure to stress, longer-lasting post-stress affective disturbance and greater risk of smoking relapse after stress than non-depressed smokers.

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Factors moderating the relative effectiveness of varenicline and nicotine replacement therapy in clients using smoking cessation services

In English stop-smoking services, the advantage of varenicline over nicotine replacement therapy is lower in pharmacy and GP settings than in specialist clinics.

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Evaluating the mutual pathways among electronic cigarette use, conventional smoking and nicotine dependence

E-cigarette use among young adults is not significantly associated with later conventional smoking, either directly or through nicotine dependence.

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Associations of parental alcohol use disorders and parental separation with offspring initiation of alcohol, cigarette and cannabis use and sexual debut in high-risk families

Parental alcohol use disorders and parental separation predict increased risk of early alcohol, tobacco and cannabis use and sexual debut in offspring from high-risk families.

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Alcohol e-Help: study protocol for web-based self-help program to reduce alcohol use in adults w/drinking patterns considered harmful, hazardous or suggestive of dependence in mid-income countries

If the World Health Organization's web-based self-help program, Alcohol e-Health, is found to be effective, its potential public health impact in countries with underdeveloped alcohol prevention and alcohol use disorder treatment systems is considerable.

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Moving alcohol prevention research forward--Part I: introducing a complex systems paradigm

A proposed complex systems paradigm for research into alcohol misuse can transcend limitations of traditional approaches and lead to high-leverage preventive interventions.

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Moving alcohol prevention research forward--Part II: new directions grounded in community-based system dynamics modeling

Community-based system dynamics modeling can provide powerful tools for policy and intervention decisions in alcohol misuse prevention.

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